Glomerular sialoprotein.

Science (New York, N.Y.) ·Vol. 164 ·No. 3887 ·1969-06-27 ·Pages 1519-21

Mohos SC, Skoza L

Abstract

The high content of sialic acid in the glomerulus is associated with the cell membrane of epithelial cells lining the basement membrane. Whereas enzyme studies indicate that sialic acid is a determinant of the nephritogenic antigen, the physicochemical properties of this nephritogenic glycoprotein suggest that sialic acid may have an important role in the filtration mechanism.

MeSH Terms

Animals Antigens Basement Membrane Cell Membrane Colloids Epithelium Female Glomerular Filtration Rate Glycoproteins Histocytochemistry Iron Kidney/immunology Kidney Glomerulus/analysis Mice Microscopy, Electron Neuraminic Acids/analysis

Chemicals

Antigens Colloids Glycoproteins Neuraminic Acids Iron

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Mohos S C

Skoza L

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.164.3887.1519

Published

1969-06-27

Pages

1519-21

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.164.3887.1519 View journal details

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