Phosphonomycin, a new antibiotic produced by strains of streptomyces.

Science (New York, N.Y.) ·Vol. 166 ·No. 3901 ·1969-10-03 ·Pages 122-3

Hendlin D, Stapley EO, Jackson M, Wallick H, Miller AK, Wolf FJ, Miller TW, Chaiet L, Kahan FM, Foltz EL, Woodruff HB, Mata JM, Hernandez S, Mochales S

Abstract

Phosphonomycin is a newly discovered antibiotic produced by streptomycetes. It is effective, when administered by the oral route, to mice infected with Gram-positive or Gram-negative microorganisms. The antibiotic is bactericidal and inhibits cell-wall synthesis.

MeSH Terms

Animals Anti-Bacterial Agents/biosynthesis,isolation & purification,pharmacology,therapeutic use Bacteria/drug effects Cell Wall/drug effects Infections/drug therapy Mice Streptomyces/metabolism

Chemicals

Anti-Bacterial Agents

Authors & Affiliations

14 authors, click to expand affiliations / ORCID

Hendlin D

Stapley E O

Jackson M

Wallick H

Miller A K

Wolf F J

Miller T W

Chaiet L

Kahan F M

Foltz E L

Woodruff H B

Mata J M

Hernandez S

Mochales S

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.166.3901.122

Published

1969-10-03

Pages

122-3

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.166.3901.122 View journal details

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Phosphonomycin, a new antibiotic produced by strains of streptomyces.

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