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PMID: 5880985 Published · ppublish English Journal Article

Interaction between the effects of inside and outside Na and K on bullfrog skin potential.

The Journal of general physiology ·Vol. 49 ·No. 2 ·1965-11-00 ·Pages 309-20

Leb DE, Edwards C, Lindley BD, Hoshiko T

Abstract

The composition of the solution bathing one border of the isolated frog skin affects the response of the potential across the skin to changes in the composition of the solution bathing the opposite border. Increasing the K concentration of the inside (corium) bathing solution decreased the sensitivity of the potential to a change in outside Na concentration. Decreasing the outside Na concentration decreased the sensitivity of the potential to a change in inside K concentration. Increasing the total ionic strength of the outside bathing solution or of both bathing solutions decreased the sensitivity of the potential to a change in outside Na concentration.

MeSH Terms
Animals Anura Electrophysiology In Vitro Techniques Potassium/pharmacology Seasons Skin/drug effects Skin Physiological Phenomena Sodium/pharmacology
Chemicals
Sodium Potassium
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Leb D E
Edwards C
Lindley B D
Hoshiko T
References (14)
14 references, click to expand
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Article Info
Journal
The Journal of general physiology
Abbr.
J Gen Physiol
ISSN
0022-1295
Published
1965-11-00
Pages
309-20
Language
English
Region
United States
NLM ID
2985110R
PMCID
PMC2195478
Subset
IM
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