Enhancement of human lymphocyte responses to phytomitogens in vitro by incubation at elevated temperatures.
Incubation of human lymphocytes with PHA or Con A at 39 degrees C for 3 days caused a consistent, statistically significant, increase in [3H]thymidine uptake, compared with cultures incubated at 37 degrees C. The responses were also significantly increased after 2 days of incubation, suggesting that hyperthermia not only enhanced, but also caused an earlier onset of the mitogen response.
8 references, click to expand
-
Different optimal temperatures for the biologic activity of rabbit and human lymphocytes in vitro.Arch Roum Pathol Exp Microbiol. 1973 Jun;32(2):297-300 PMID: 4356237
-
Effect of viral and bacterial pneumonias on cell-mediated immunity in humans.Infect Immun. 1976 Jan;13(1):78-83 PMID: 1082445
-
The Ferrier Lecture, 1974. Body temperature and fever: changes in our views during the last decade.Proc R Soc Lond B Biol Sci. 1975 Nov 18;191(1103):199-229 PMID: 2913
-
Temperature optimum and rabbit blood cell culture.Acta Pathol Microbiol Scand B Microbiol Immunol. 1972;80(5):775-6 PMID: 4508787
-
The effects of cell density, incubation temperature, syngeneic serum, and syngeneic red blood cells on mouse lymphocyte responses in vitro.J Immunol Methods. 1975 Dec;9(2):171-84 PMID: 128572
-
Effects of incubation temperature on the kinetics of cultured lymphocytes from the opossum, Didelphis virginiana.Experientia. 1974 Oct 15;30(10):1192-3 PMID: 4435132
-
A micromethod for stimulation of lymphocytes by phytohaemagglutinin.Aust J Exp Biol Med Sci. 1972 Oct;50(5):603-9 PMID: 4651118
-
[Effect of temperature on the mitotic activity of cultured human peripheral blood lymphocytes].Biull Eksp Biol Med. 1972 Dec;73(12):87-8 PMID: 4642777
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