Postnatal development of adrenergic and cholinergic sensitivity in the isolated rat atria.

Experientia ·Vol. 33 ·No. 12 ·1977-12-15 ·Pages 1611-12

Nukari-Siltovuori A

Abstract

The sensitivity to adrenergic drugs in isolated rat atria increased with the postnatal development. The cholinergic chronotropic sensitivity did not further change after birth.

MeSH Terms

Acetylcholine/pharmacology Aging Animals Carbachol/pharmacology Heart/drug effects Heart Atria Isoproterenol/pharmacology Male Norepinephrine/pharmacology Parasympathomimetics/pharmacology Phenylephrine/pharmacology Rats Sympathomimetics/pharmacology

Chemicals

Parasympathomimetics Sympathomimetics Phenylephrine Carbachol Isoproterenol Acetylcholine Norepinephrine

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Nukari-Siltovuori A

References (11)

11 references, click to expand

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Ontogenesis of peripheral adrenergic neurons in the rat: pre- and postnatal observations.
Acta Physiol Scand. 1970 Oct;80(2):276-88 PMID: 5475346
Responses to hypothermia in several species of infant mammals.
Am J Physiol. 1951 Jul;166(1):75-91 PMID: 14857150
PHYSIOLOGICAL DISPOSITION OF H3-NOREPINEPHRINE IN THE DEVELOPING RAT.
J Pharmacol Exp Ther. 1964 Oct;146:48-53 PMID: 14221225
Acetylcholine and epinephrine effects on the embryonic rat heart.
J Cell Comp Physiol. 1957 Apr;49(2):187-200 PMID: 13481061
Cumulative dose-response curves. II. Technique for the making of dose-response curves in isolated organs and the evaluation of drug parameters.
Arch Int Pharmacodyn Ther. 1963;143:299-330 PMID: 13996119
Postnatal ontogenetic development of neurogenic and myogenic control in the rat portal vein.
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Article Info

Journal

Experientia

Abbr.

Experientia

ISSN

0014-4754

DOI

10.1007/BF01934027

Published

1977-12-15

Pages

1611-12

Language

English

Region

Switzerland

NLM ID

0376547

Subset

External Links

PubMed source DOI: 10.1007/BF01934027

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Postnatal development of adrenergic and cholinergic sensitivity in the isolated rat atria.

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