Glucagon resistance as a case of hypertriglyceridaemia.

The hypothesis that glucagon resistance is a cause of hypertriglyceridaemia has been tested by studying the effects of exogenous glucagon in patients with hypertriglyceridaemia and controls. Glucagon and a greater triglyceride-lowering-effect in hypertriglyceridaemic patients than in controls. The other metabolic response to glucagon were similar in both groups. No evidence of glucagon resistance was found.