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PMID: 5945246 Published · ppublish English Journal Article

Potentiometric measurement of membrane action potentials in frog muscle fibres.

The Journal of physiology ·Vol. 183 ·No. 1 ·1966-03-00 ·Pages 152-66

Frankenhaeuser B, Lindley BD, Smith RS

Abstract

1. A potentiometric method for recording membrane action potentials from small segments of isolated skeletal muscle fibres has been described.2. The value of the method in muscle physiology has been appraised by recording from fast and slow skeletal muscle fibres of the frog under a variety of conditions.3. Artifacts associated with this method have been described and their sources investigated.

MeSH Terms
Animals Anura Cell Membrane/physiology Electrophysiology In Vitro Techniques Muscles/physiology Potentiometry
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Frankenhaeuser B
Lindley B D
Smith R S
References (5)
5 references, click to expand
  1. Membrane potentials of the lobster giant axon obtained by use of the sucrose-gap technique.
    J Gen Physiol. 1962 Jul;45:1195-216 PMID: 14452759
  2. Direct determination of membrane resting potential and action potential in single myelinated nerve fibers.
    J Physiol. 1951 Feb;112(3-4):476-95 PMID: 14825228
  3. The electrical properties of the slow muscle fibre membrane.
    J Physiol. 1956 Jun 28;132(3):586-98 PMID: 13332596
  4. Membrane currents in isolated frog nerve fibre under voltage clamp conditions.
    J Physiol. 1958 Aug 29;143(1):76-90 PMID: 13576461
  5. A method for recording resting and action potentials in the isolated myelinated nerve fibre of the frog.
    J Physiol. 1957 Mar 11;135(3):550-9 PMID: 13417121
Article Info
Journal
The Journal of physiology
Abbr.
J Physiol
ISSN
0022-3751
Published
1966-03-00
Pages
152-66
Language
English
Region
England
NLM ID
0266262
PMCID
PMC1357533
Subset
IM
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