The release of adenosine triphosphate catabolites during the secretion of catecholamines by bovine adrenal medulla.

The Biochemical journal ·Vol. 101 ·No. 2 ·1966-11-00 ·Pages 536-41

Banks P

Abstract

1. AMP, adenosine, inosine and hypoxanthine were present in perfusates collected from bovine adrenal glands during periods when catecholamine secretion was evoked by injections of carbamoylcholine. 2. The molar ratio of catecholamines to ATP-catabolites present in the perfusates was similar to that of catecholamines to ATP in chromaffin granules. 3. ATP added to the perfusing medium was extensively degraded during passage through bovine adrenal glands. 4. The mechanism of catecholamine secretion is discussed.

MeSH Terms

Adenine Nucleotides/metabolism Adenosine Triphosphate/metabolism Adrenal Medulla/physiology Animals Catecholamines/physiology Cattle Chromatography, Ion Exchange Electrophoresis Hypoxanthines/metabolism In Vitro Techniques Nucleosides/metabolism Perfusion

Chemicals

Adenine Nucleotides Catecholamines Hypoxanthines Nucleosides Adenosine Triphosphate

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Banks P

References (13)

13 references, click to expand

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On the relation between ATP splitting and secretion in the adrenal chromaffin cell: extrusion of ATP (unhydrolysed) during release of catecholamines.
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Article Info

Journal

The Biochemical journal

Abbr.

Biochem J

ISSN

0264-6021

DOI

10.1042/bj1010536

Published

1966-11-00

Pages

536-41

Language

English

Region

England

NLM ID

2984726R

PMCID

PMC1270137

Subset

External Links

PubMed source DOI: 10.1042/bj1010536 PMC Full Text View journal details

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The release of adenosine triphosphate catabolites during the secretion of catecholamines by bovine adrenal medulla.

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