Cation movements in the high sodium erythrocyte of the cat.

The Journal of general physiology ·Vol. 50 ·No. 6 ·1967-07-00 ·Pages 1751-64

Sha'afi RI, Lieb WR

Abstract

The uptake of (42)K and (24)Na by cat erythrocytes was investigated. Under steady-state conditions, the nontransient component of (42)K influx was found to be 0.18 +/- 0.01 meq/liter RBC/hr and insensitive to ouabain (100 microM); the corresponding value for (24)Na was 17 +/- meq/liter RBC/hr. A study was made of the effects of anions upon cation movements in these and other mammalian red cells. Iodide was found to inhibit markedly (>50%) Na inward movements in cat and dog but not in the other erythrocytes. An increase (15-30%) in K uptake in the presence of iodide was noted in all the mammalian cells studied.

MeSH Terms

Animals Biological Transport, Active/physiology Cats Cell Membrane Permeability/drug effects Dogs Erythrocytes/metabolism Iodides/pharmacology Models, Theoretical Ouabain/pharmacology Potassium/metabolism Potassium Isotopes Rabbits Sheep Sodium/metabolism Sodium Isotopes

Chemicals

Iodides Potassium Isotopes Sodium Isotopes Ouabain Sodium Potassium

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Sha'afi R I

Lieb W R

References (6)

6 references, click to expand

Potassium and sodium balance in mammalian red cells.
Science. 1954 Sep 17;120(3116):459-60 PMID: 13195674
The influence of the lyotropic series of anions on cation permeability.
Biochem J. 1940 Jun;34(6):917-25 PMID: 16747236
Potassium transport in human erythrocytes: evidence for a three compartment system.
J Gen Physiol. 1955 Jan 20;38(3):371-88 PMID: 13221778
The permeability of the human erythrocyte to sodium and potassium.
J Gen Physiol. 1952 May;36(1):57-110 PMID: 12981235
Regulation of cell volume by active cation transport in high and low potassium sheep red cells.
J Gen Physiol. 1960 Sep;44:169-94 PMID: 13777653
The action of cardiac glycosides on sodium and potassium movements in human red cells.
J Physiol. 1957 Apr 3;136(1):148-73 PMID: 13417139

Article Info

Journal

The Journal of general physiology

Abbr.

J Gen Physiol

ISSN

0022-1295

DOI

10.1085/jgp.50.6.1751

Published

1967-07-00

Pages

1751-64

Language

English

Region

United States

NLM ID

2985110R

PMCID

PMC2225730

Subset

External Links

PubMed source DOI: 10.1085/jgp.50.6.1751 PMC Full Text View journal details

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Cation movements in the high sodium erythrocyte of the cat.

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