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PMID: 6051797 Published · ppublish English Journal Article

Evidence for the presence of 16 alpha-hydroxypregn-4-ene-3,20-dione in adrenal venous blood of young pigs.

The Journal of physiology ·Vol. 191 ·No. 3 ·1967-08-00 ·Pages 691-7

Holzbauer M, Newport HM

Abstract

1. Evidence was obtained for the presence of 16alpha-hydroxypregn-4-ene-3,20-dione in each adrenal venous blood sample collected from eight young pigs under conditions of operative stress.2. The chemical identity of this steroid was tested on mug amounts by paper and gas chromatographic methods before and after the formation of derivatives.

MeSH Terms
Adrenal Glands/metabolism Animals Chromatography, Gas Chromatography, Paper Dogs Female Hydroxyprogesterones/blood,metabolism Male Stress, Physiological Swine
Chemicals
Hydroxyprogesterones
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Holzbauer M
Newport H M
References (11)
11 references, click to expand
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    J Endocrinol. 1966 Oct;36(2):159-76 PMID: 4224178
  2. Metabolism of progesterone by the perfused previable human fetus.
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  3. Metabolism of progesterone by the perfused adrenalectomized human fetus.
    J Clin Endocrinol Metab. 1966 Oct;26(10):1155-9 PMID: 5923697
  4. Methods of paper chromatography of steroids applicable to the study of steroids in mammalian blood and tissues.
    Biochem J. 1952 Jan;50(3):370-8 PMID: 14915960
  5. The corticosterone content of rat adrenals under different experimental conditions.
    J Physiol. 1957 Dec 3;139(2):294-305 PMID: 13492213
  6. Corticosteroids in plasma and cells of adrenal venous blood.
    J Physiol. 1961 Jun;157:137-56 PMID: 13715600
  7. [Use of Huebener's 20 beta-hydroxysteroid dehydrogenase in the microchemical identification and separation of steroids].
    Hoppe Seylers Z Physiol Chem. 1962 Dec 15;330:31-7 PMID: 13953773
  8. A fluorimetric method for the estimation of 4-hydroxy-3-methoxyphenylacetic acid (homovanillic acid) and its identification in brain tissue.
    Br J Pharmacol Chemother. 1963 Feb;20:204-13 PMID: 13976893
  9. THE PART PLAYED BY ACTH IN DETERMINING THE RATE OF ALDOSTERONE SECRETION DURING OPERATIVE STRESS.
    J Physiol. 1964 Jul;172:138-49 PMID: 14195688
  10. A FLUORESCENCE ASSAY OF PROGESTERONE.
    J Endocrinol. 1964 Oct;30:293-305 PMID: 14225229
  11. New solvent systems for the resolution of corticosteroids by paper chromatography.
    Arch Biochem Biophys. 1955 Nov;59(1):90-6 PMID: 13269159
Article Info
Journal
The Journal of physiology
Abbr.
J Physiol
ISSN
0022-3751
DOI
10.1113/jphysiol.1967.sp008275
Published
1967-08-00
Pages
691-7
Language
English
Region
England
NLM ID
0266262
PMCID
PMC1365499
Subset
IM
External Links
PubMed source DOI: 10.1113/jphysiol.1967.sp008275 PMC Full Text View journal details
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