Enzyme concentrations in tissues.

Science (New York, N.Y.) ·Vol. 158 ·No. 3803 ·1967-11-17 ·Pages 936-7

Srere PA

Abstract

Apparent enzyme concentrations in cells and in mitochondria are calculated from data available in the literature. These values are 10(-6) to 10(-5) moles per kilogram of tissue. It is pointed out that these concentrations are much higher than those used in enzymatic studies in vitro. Metabolic interpretations of experiments in vitro should consider this additional departure from conditions in vivo.

MeSH Terms

Animals Biometry Cytochromes/analysis Dihydrolipoamide Dehydrogenase/analysis Dogs Enzymes/analysis Fructose-Bisphosphate Aldolase/analysis Glucosephosphate Dehydrogenase/analysis Hydro-Lyases/analysis Isocitrate Dehydrogenase/analysis Ligases/analysis Malate Dehydrogenase/analysis Mitochondria/enzymology Myocardium/enzymology Rabbits Rats Swine

Chemicals

Cytochromes Enzymes Malate Dehydrogenase Isocitrate Dehydrogenase Glucosephosphate Dehydrogenase Dihydrolipoamide Dehydrogenase Fructose-Bisphosphate Aldolase Hydro-Lyases Ligases

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Srere P A

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.158.3803.936

Published

1967-11-17

Pages

936-7

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.158.3803.936 View journal details

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