Home LiteratureArticle Details

PMID: 6097248 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Cloning of genomic DNA for human atrial natriuretic factor.

Biochemical and biophysical research communications ·Vol. 125 ·No. 2 ·1984-12-14 ·Pages 797-802

Maki M, Parmentier M, Inagami T

Abstract

A human genomic DNA clone for atrial natriuretic factor (ANF) gene was isolated from a human gene library using the previously cloned cDNA for rat ANF as a probe. Partial nucleotide sequencing of the cloned DNA revealed the location of a 120-bp long intron between Lys-41 and Asn-42 of the ANF precursor. Restriction mapping also suggested the existence of at least one other intron in or proximal to the 3' -untranslated region.

MeSH Terms

Amino Acid Sequence Animals Atrial Natriuretic Factor Bacteriophage lambda/metabolism Base Sequence Cloning, Molecular DNA/isolation & purification DNA Restriction Enzymes Female Fetus Genes Humans Liver/metabolism Muscle Proteins/genetics Nucleic Acid Hybridization Pregnancy Rats Species Specificity

Chemicals

Muscle Proteins NPPA protein, human Atrial Natriuretic Factor DNA DNA Restriction Enzymes

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Maki M

Parmentier M

Inagami T

Article Info

Journal

Biochemical and biophysical research communications

Abbr.

Biochem Biophys Res Commun

ISSN

0006-291X

DOI

10.1016/0006-291x(84)90609-0

Published

1984-12-14

Pages

797-802

Language

English

Region

United States

NLM ID

0372516

Subset

Grants

NHLBI NIH HHS · HL-14192 · United States

NHLBI NIH HHS · HL-22288 · United States

NHLBI NIH HHS · HL-24112 · United States

Databases

GENBANK

K02399

External Links

PubMed source DOI: 10.1016/0006-291x(84)90609-0 View journal details

Analysis Services

Cloning of genomic DNA for human atrial natriuretic factor.

Contact

WeChat Official Account