Home LiteratureArticle Details
PMID: 6127317 Published · ppublish English Journal Article

Interleukin 2 induction in Lyt 1+ 23- T cells from Listeria monocytogenes-immune mice.

Infection and immunity ·Vol. 37 ·No. 3 ·1982-09-00 ·Pages 1292-4

Kaufmann SH, Hahn H, Simon MM, Röllinghoff M, Wagner H

Abstract

Peritoneal exudate T lymphocytes from mice experimentally infected with the intracellular bacterium Listeria monocytogenes secreted high interleukin 2 activities after interaction with syngeneic normal macrophage presenting listerial antigen in vitro. L. monocytogenes-immune cells secreting IL 2 were radioresistant and bore the phenotype Thy 1(+) Lyt 1(+)23(-).

MeSH Terms
Animals Antigens, Bacterial Antigens, Ly Antigens, Surface Interleukin-2/metabolism Listeria monocytogenes/immunology Listeriosis/immunology Macrophages/immunology Mice Phenotype T-Lymphocytes/immunology,metabolism Thy-1 Antigens
Chemicals
Antigens, Bacterial Antigens, Ly Antigens, Surface Interleukin-2 Thy-1 Antigens
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Kaufmann S H
Hahn H
Simon M M
Röllinghoff M
Wagner H
References (12)
12 references, click to expand
  1. A rapid method for the isolation of functional thymus-derived murine lymphocytes.
    Eur J Immunol. 1973 Oct;3(10):645-9 PMID: 4587740
  2. Lymphocytes as models for the study of mammalian cellular differentiation.
    Immunol Rev. 1977 Jan;33:105-24 PMID: 300350
  3. Molecular and quantitative analysis of helper T cell-replacing factors on the induction of antigen-sensitive B and T lymphocytes.
    J Immunol. 1979 May;122(5):1633-8 PMID: 109511
  4. The specific binding of Listeria monocytogenes-immune T lymphocytes to macrophages. I. Quantitation and role of H-2 gene products.
    J Exp Med. 1979 Nov 1;150(5):1143-60 PMID: 115958
  5. Murine lymphocyte surface antigens.
    Adv Immunol. 1979;27:179-338 PMID: 92182
  6. Specific Lyt 123 cells are involved in protection against Listeria monocytogenes and in delayed-type hypersensitivity to listerial antigens.
    J Exp Med. 1979 Oct 1;150(4):1033-8 PMID: 117073
  7. T-T cell interactions during in vitro cytotoxic T lymphocyte (CTL) responses. II. Helper factor from activated Lyt 1+ T cells is rate limiting i) in T cell responses to nonimmunogenic alloantigen, ii) in thymocyte responses to allogeneic stimulator cells, and III) recruits allo- or H-2-restricted CTL precursors from the Lyt 123+ T subset.
    J Immunol. 1980 Mar;124(3):1058-67 PMID: 6766966
  8. Intrathymic differentiation of cytotoxic T lymphocyte (CTL) precursors. I. The CTL immunocompetence of peanut agglutinin-positive (cortical) and negative (medullary) Lyt 123 thymocytes.
    J Immunol. 1980 Dec;125(6):2532-8 PMID: 6159411
  9. Lyt-23+ cyclophosphamide-sensitive T cells regulate the activity of an interleukin 2 inhibitor in vivo.
    J Exp Med. 1981 Aug 1;154(2):262-74 PMID: 6790656
  10. T cell subsets participating in the generation of cytotoxic T cells.
    Springer Semin Immunopathol. 1980 May;3(1):39-62 PMID: 6169168
  11. The role of cell-mediated immunity in bacterial infections.
    Rev Infect Dis. 1981 Nov-Dec;3(6):1221-50 PMID: 6805064
  12. T lymphocyte-macrophage interactions in cellular antibacterial immunity.
    Immunobiology. 1982 Apr;161(3-4):361-8 PMID: 6807832
Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
Published
1982-09-00
Pages
1292-4
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC347679
Subset
IM
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]