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PMID: 61284 Published · ppublish English Comparative Study Journal Article Research Support, U.S. Gov't, P.H.S.

Assay for type C virus in mouse sera based on particulate reverse transcriptase activity.

Journal of virology ·Vol. 19 ·No. 3 ·1976-09-00 ·Pages 1107-10

Roy-Burman P, Dougherty M, Pal BK, Charman HP, Klement V, Gardner MB

Abstract

Assay of particulate reverse transcriptase activity in the sera from feral mice naturally infected with type C virus provides a sensitive and rapid procedure for the determination of in vivo virus infection. The results compare well with assays for infectious virus and with complement fixation or competitive radio-immunoassays for the p30 internal antigen of the virus.

MeSH Terms

Animals Complement Fixation Tests Evaluation Studies as Topic Gammaretrovirus/enzymology Mice RNA-Directed DNA Polymerase/blood Radioimmunoassay Retroviridae/enzymology Tumor Virus Infections/diagnosis

Chemicals

RNA-Directed DNA Polymerase

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Roy-Burman P

Dougherty M

Pal B K

Charman H P

Klement V

Gardner M B

References (14)

14 references, click to expand

Clonal cells lines from a feral mouse embryo which lack host-range restrictions for murine leukemia viruses.
Virology. 1975 May;65(1):128-34 PMID: 167514
Biochemical properties of wild mouse oncornaviruses with lymphomagenic and neurotropic activities.
Bibl Haematol. 1975;(40):627-37 PMID: 169831
The epidemiology and virology of C-type virus-associated hematological cancers and related diseases in wild mice.
Cancer Res. 1976 Feb;36(2 pt 2):574-81 PMID: 175918
Coexistence of intraspecies and interspecies specific antigenic determinants on the major structural polypeptide of mammalian C-type viruses.
Nat New Biol. 1971 May 26;231(21):107-8 PMID: 4103327
Viral and cellular DNA polymerase: comparison of activities with synthetic and natural RNA templates.
Science. 1972 May 19;176(4036):798-800 PMID: 4113240
Subviral components of a wild mouse embryo-derived type C oncornavirus.
Virology. 1973 Nov;56(1):189-97 PMID: 4126842
Radioimmunoassay for the major structural protein of hamster type C viruses.
J Virol. 1974 Oct;14(4):910-7 PMID: 4138682
Complement fixation and tissue culture assays for mouse leukemia viruses.
Proc Natl Acad Sci U S A. 1965 May;53(5):931-8 PMID: 4287967
RNA-dependent DNA polymerase in virions of RNA tumour viruses.
Nature. 1970 Jun 27;226(5252):1209-11 PMID: 4316300
RNA-dependent DNA polymerase in virions of Rous sarcoma virus.
Nature. 1970 Jun 27;226(5252):1211-3 PMID: 4316301
Primer requirement and template specificity of the DNA polymerase of RNA tumor viruses.
Proc Natl Acad Sci U S A. 1971 Jul;68(7):1507-11 PMID: 4327004
Distinguishing reverse transcriptase of an RNA tumor virus from other known DNA polymerases.
Proc Natl Acad Sci U S A. 1971 Sep;68(9):2203-6 PMID: 4332248
A spontaneous lower motor neuron disease apparently caused by indigenous type-C RNA virus in wild mice.
J Natl Cancer Inst. 1973 Oct;51(4):1243-54 PMID: 4355605
RNA metabolism of murine leukemia virus: detection of virus-specific RNA sequences in infected and uninfected cells and identification of virus-specific messenger RNA.
J Mol Biol. 1973 Oct 15;80(1):93-117 PMID: 4798989

Article Info

Journal

Journal of virology

Abbr.

J Virol

ISSN

0022-538X

DOI

10.1128/JVI.19.3.1107-1110.1976

Published

1976-09-00

Pages

1107-10

Language

English

Region

United States

NLM ID

0113724

PMCID

PMC354951

Subset

External Links

PubMed source DOI: 10.1128/JVI.19.3.1107-1110.1976 PMC Full Text View journal details

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Assay for type C virus in mouse sera based on particulate reverse transcriptase activity.

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