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PMID: 6131381 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Review

Calcium channel modulation by neurotransmitters, enzymes and drugs.

Nature ·Vol. 301 ·No. 5901 ·1983-00-00 ·Pages 569-74

Reuter H

Abstract

Calcium channels in excitable membranes are of great importance for many cellular functions. Modulation of these channels by neurotransmitters and drugs regulates calcium influx into the cell and thereby alters the functional state of the cell. Recently it has become possible to measure properties of single calcium channels directly and to obtain evidence on mechanisms of their modulation.

MeSH Terms

Animals Aplysia Calcium/metabolism Calcium Channel Blockers/pharmacology Cell Membrane Permeability Cyclic AMP/metabolism Humans Ion Channels/drug effects Kinetics Membrane Proteins/metabolism Models, Biological Myocardium/metabolism Neurons/metabolism Neurotransmitter Agents/pharmacology Phosphorylation Receptors, Adrenergic, beta/metabolism Verapamil/pharmacology

Chemicals

Calcium Channel Blockers Ion Channels Membrane Proteins Neurotransmitter Agents Receptors, Adrenergic, beta Verapamil Cyclic AMP Calcium

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Reuter H

Article Info

Journal

Nature

Abbr.

Nature

ISSN

0028-0836

DOI

10.1038/301569a0

Published

1983-00-00

Pages

569-74

Language

English

Region

England

NLM ID

0410462

Subset

External Links

PubMed source DOI: 10.1038/301569a0 View journal details

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