Angiogenesis factor from human myocardial infarcts.

Lancet (London, England) ·Vol. 2 ·No. 8346 ·1983-08-13 ·Pages 364-8

Kumar S, West D, Shahabuddin S, Arnold F, Haboubi N, Reid H, Carr T

Abstract

5 of 8 infarcted human myocardial tissues were shown to contain an angiogenesis factor which resembles that obtained from solid tumours. The concentration of angiogenesis factor, measured by radioimmunoassay, was similar to that in tumours. It is suggested that the myocardial-infarct angiogenesis factor modulates collateral enlargement or ingrowth of new blood vessels in the infarcted tissues.

MeSH Terms

Aged Angiogenesis Inducing Agents/metabolism Animals Antigens, Neoplasm/immunology Capillaries/growth & development Cross Reactions Dogs Growth Substances/metabolism Humans Middle Aged Models, Biological Myocardial Infarction/metabolism Myocardium/immunology,metabolism Neoplasms/blood supply,metabolism Radioimmunoassay Rats

Chemicals

Angiogenesis Inducing Agents Antigens, Neoplasm Growth Substances

Authors & Affiliations

7 authors, click to expand affiliations / ORCID

Kumar S

West D

Shahabuddin S

Arnold F

Haboubi N

Reid H

Carr T

Article Info

Journal

Lancet (London, England)

Abbr.

Lancet

ISSN

0140-6736

DOI

10.1016/s0140-6736(83)90343-4

Published

1983-08-13

Pages

364-8

Language

English

Region

England

NLM ID

2985213R

Subset

External Links

PubMed source DOI: 10.1016/s0140-6736(83)90343-4 View journal details

Analysis Services

Angiogenesis factor from human myocardial infarcts.

Contact

WeChat Official Account