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PMID: 6140548 Published · ppublish English Journal Article

Aetiology of Parkinson's disease.

Lancet (London, England) ·Vol. 2 ·No. 8365-66 ·1983-00-00 ·Pages 1457-9

Calne DB, Langston JW

Abstract

It is suggested here that in most cases of Parkinson's disease the cause may be an environmental factor, possibly toxic, superimposed on a background of slow, sustained neuronal loss due to advancing age.

MeSH Terms
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Aging Animals Diseases in Twins Environmental Exposure Humans Models, Neurological Neurotoxins/poisoning Parkinson Disease/etiology,genetics Pyridines/poisoning Virus Diseases/complications
Chemicals
Neurotoxins Pyridines 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Calne D B
Langston J W
Article Info
Journal
Lancet (London, England)
Abbr.
Lancet
ISSN
0140-6736
DOI
10.1016/s0140-6736(83)90802-4
Published
1983-00-00
Pages
1457-9
Language
English
Region
England
NLM ID
2985213R
Subset
IM
External Links
PubMed source DOI: 10.1016/s0140-6736(83)90802-4 View journal details
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