Preparation of covalently linked immune complexes of specific composition.

Journal of immunological methods ·Vol. 33 ·No. 1 ·1980-00-00 ·Pages 55-61

Chan EK, Boyd ND

Abstract

Covalently linked soluble immune complexes were prepared with a 2-stage bifunctional reagent. Complexes with antigen-antibody ratio 2 : 1 were purified and characterized. The covalent linkage and antigenic characteristics of the complexes were demonstrated.

MeSH Terms

Animals Antigen-Antibody Complex Cattle Chromatography, Agarose Cross-Linking Reagents Cyanates/pharmacology Goats Immune Complex Diseases/immunology Molecular Weight Rabbits Serum Albumin, Bovine/immunology Toluene 2,4-Diisocyanate/pharmacology gamma-Globulins/immunology

Chemicals

Antigen-Antibody Complex Cross-Linking Reagents Cyanates gamma-Globulins Toluene 2,4-Diisocyanate Serum Albumin, Bovine

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Chan E K

Boyd N D

Article Info

Journal

Journal of immunological methods

Abbr.

J Immunol Methods

ISSN

0022-1759

DOI

10.1016/0022-1759(80)90082-4

Published

1980-00-00

Pages

55-61

Language

English

Region

Netherlands

NLM ID

1305440

Subset

External Links

PubMed source DOI: 10.1016/0022-1759(80)90082-4 View journal details

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Preparation of covalently linked immune complexes of specific composition.

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