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PMID: 6163712 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Immunochemical properties of Vi antigen from Salmonella typhi Ty2: presence of two antigenic determinants.

Infection and immunity ·Vol. 29 ·No. 2 ·1980-08-00 ·Pages 539-44

Szewczyk B, Taylor A

Abstract

Antigen Vi of Salmonella typhi was found to have at least two antigenic determinants. In one of them, O-acetyl moiety played a dominant role. The second antigenic determinant did not involve O-acetyl residues, but both carboxyl and N-acetyl groups were necessary for the antigen-antibody reaction. These results were obtained by performing serological tests with antigen Vi, with its structural analog, polygalacturonic acid, and with the derivatives of both polysaccharides.

MeSH Terms
Antigens, Bacterial/immunology Epitopes/immunology Hemagglutination Inhibition Tests Hemagglutination Tests Immune Sera Precipitin Tests Salmonella typhi/immunology
Chemicals
Antigens, Bacterial Epitopes Immune Sera
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Szewczyk B
Taylor A
References (12)
12 references, click to expand
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Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/iai.29.2.539-544.1980
Published
1980-08-00
Pages
539-44
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC551152
Subset
IM
External Links
PubMed source DOI: 10.1128/iai.29.2.539-544.1980 PMC Full Text View journal details
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