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PMID: 6166781 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Retinoic acid: enhancement of a tumor and inhibition of interferon's antitumor action.

Journal of the National Cancer Institute ·Vol. 67 ·No. 1 ·1981-07-00 ·Pages 95-7

Baron S, Kleyn KM, Russell JK, Blalock JE

Abstract

The effect of trans-retinoic acid on the growth of P388 lymphoid tumors in inbred female DBA/2 mice in the presence or absence of interferon (FN) treatment was studied. This acid derivative of vitamin A enhanced local tumor growth. trans-retinoic acid also partially reversed IFN protection against tumor growth and mortality.

MeSH Terms

Animals Cell Line Female Interferons/antagonists & inhibitors Mice Mice, Inbred DBA Neoplasm Transplantation Neoplasms, Experimental/therapy Time Factors Tretinoin/pharmacology

Chemicals

Tretinoin Interferons

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Baron S

Kleyn K M

Russell J K

Blalock J E

Article Info

Journal

Journal of the National Cancer Institute

Abbr.

J Natl Cancer Inst

ISSN

0027-8874

Published

1981-07-00

Pages

95-7

Language

English

Region

United States

NLM ID

7503089

Subset

External Links

PubMed source View journal details

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Retinoic acid: enhancement of a tumor and inhibition of interferon's antitumor action.

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