Home LiteratureArticle Details
PMID: 6174938 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Improvements to a program for DNA analysis: a procedure to find homologies among many sequences.

Nucleic acids research ·Vol. 10 ·No. 1 ·1982-01-11 ·Pages 449-56

Queen C, Wegman MN, Korn LJ

Abstract

We have devised an algorithm for finding partial homologies among a set of nucleotide sequences. The algorithm and other improvements have been incorporated into a commonly used computer program for the analysis of sequence data.

MeSH Terms
Base Sequence Computers DNA Methods RNA Ribonuclease T1
Chemicals
RNA DNA Ribonuclease T1
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Queen C
Wegman M N
Korn L J
References (35)
35 references, click to expand
  1. Nucleotide sequence of an RNA polymerase binding site from the DNA of bacteriophage fd.
    Proc Natl Acad Sci U S A. 1975 Feb;72(2):737-41 PMID: 1054851
  2. Nucleotide sequence of an RNA polymerase binding site at an early T7 promoter.
    Proc Natl Acad Sci U S A. 1975 Mar;72(3):784-8 PMID: 1093168
  3. Computer analysis of nucleic acid regulatory sequences.
    Proc Natl Acad Sci U S A. 1977 Oct;74(10):4401-5 PMID: 270683
  4. A rho-dependent termination site in the gene coding for tyrosine tRNA su3 of Escherichia coli.
    Nature. 1978 Mar 30;272(5652):423-8 PMID: 345126
  5. Complete nucleotide sequence of SV40 DNA.
    Nature. 1978 May 11;273(5658):113-20 PMID: 205802
  6. The sequence of the chromosomal mouse beta-globin major gene: homologies in capping, splicing and poly(A) sites.
    Cell. 1978 Dec;15(4):1125-32 PMID: 569555
  7. Nucleotide sequence of Xenopus borealis oocyte 5S DNA: comparison of sequences that flank several related eucaryotic genes.
    Cell. 1978 Dec;15(4):1145-56 PMID: 264240
  8. Sequence of the 16 S-23 s spacer region in two ribosomal RNA operons of Escherichia coli.
    J Biol Chem. 1979 May 10;254(9):3264-71 PMID: 372188
  9. Structure of simian virus 40 recombinants that contain both host and viral DNA sequences. II. The structure of variant 1103 and its comparison to variant CVPS/1P2 (EcoRI res).
    J Biol Chem. 1979 May 10;254(9):3592-7 PMID: 218975
  10. Nucleotide sequence of cloned cDNA for bovine corticotropin-beta-lipotropin precursor.
    Nature. 1979 Mar 29;278(5703):423-7 PMID: 221818
  11. Nucleotide sequence of the ribosomal protein gene cluster adjacent to the gene for RNA polymerase subunit beta in Escherichia coli.
    Proc Natl Acad Sci U S A. 1979 Apr;76(4):1697-701 PMID: 377281
  12. Isolation of recombinant plasmids bearing cDNA to hen ovomucoid and lysozyme mRNAs.
    J Biol Chem. 1979 Sep 25;254(18):9277-83 PMID: 383714
  13. Nucleotide sequence of the Hind-C fragment of simian virus 40 DNA. Comparison of the 5'-untranslated region of wild-type virus and of some deletion Mutants.
    Eur J Biochem. 1979 Oct;100(1):51-60 PMID: 226361
  14. The nucleotide sequence of the initiation and termination sites for ribosomal RNA transcription in X. laevis.
    Cell. 1979 Oct;18(2):485-99 PMID: 498280
  15. Deoxyribonucleic acid sequence homologies among bacterial insertion sequence elements and genomes of various organisms.
    J Bacteriol. 1979 Nov;140(2):588-96 PMID: 159291
  16. Structure and genomic organization of the mouse dihydrofolate reductase gene.
    Cell. 1980 Feb;19(2):355-64 PMID: 6244105
  17. Mechanism of mitochondrial DNA replication in mouse L-cells: localization and sequence of the light-strand origin of replication.
    J Mol Biol. 1979 Dec 5;135(2):327-51 PMID: 537081
  18. Sequence and sequence variation within the 1.688 g/cm3 satellite DNA of Drosophila melanogaster.
    J Mol Biol. 1979 Dec 5;135(2):465-81 PMID: 231676
  19. Regulatory sequences involved in the promotion and termination of RNA transcription.
    Annu Rev Genet. 1979;13:319-53 PMID: 94251
  20. Computer analysis of nucleic acids and proteins.
    Methods Enzymol. 1980;65(1):595-609 PMID: 6154871
  21. Deletions of distal sequence after termination of transcription at the end of the tryptophan operon in E. coli.
    Cell. 1980 Apr;19(4):829-36 PMID: 6991123
  22. Analysis of a drosophila tRNA gene cluster.
    Cell. 1980 Apr;19(4):889-95 PMID: 6769590
  23. Sequence of retrovirus provirus resembles that of bacterial transposable elements.
    Nature. 1980 Jun 19;285(5766):550-4 PMID: 6250038
  24. Steps toward computer analysis of nucleotide sequences.
    Science. 1980 Sep 19;209(4463):1322-8 PMID: 6251542
  25. Dictyostelium small nuclear RNA D2 is homologous to rat nucleolar RNA U3 and is encoded by a dispersed multigene family.
    Cell. 1980 Nov;22(1 Pt 1):109-18 PMID: 6159098
  26. Cloned human and mouse kappa immunoglobulin constant and J region genes conserve homology in functional segments.
    Cell. 1980 Nov;22(1 Pt 1):197-207 PMID: 6775818
  27. Secondary structures for splice junctions in eukaryotic and viral messenger RNA precursors.
    Nucleic Acids Res. 1980 Aug 25;8(16):3659-72 PMID: 6253906
  28. Structure, organization and evolution of developmentally regulated chorion genes in a silkmoth.
    Cell. 1980 Dec;22(3):855-67 PMID: 7460015
  29. DNA sequences of structural genes for Eco RI DNA restriction and modification enzymes.
    J Biol Chem. 1981 Mar 10;256(5):2131-9 PMID: 6257701
  30. Nucleotide sequences of the trpG regions of Escherichia coli, Shigella dysenteriae, Salmonella typhimurium and Serratia marcescens.
    J Mol Biol. 1980 Oct 5;142(4):503-17 PMID: 7007652
  31. A conversational system for the computer analysis of nucleic acid sequences.
    Nucleic Acids Res. 1981 Jan 24;9(2):437-44 PMID: 6163137
  32. An eleven-base-pair sequence determines the specificity of DNA uptake in Haemophilus transformation.
    Gene. 1980 Nov;11(3-4):311-8 PMID: 6260577
  33. Nucleotide sequence of the initiation site for ribosomal RNA transcription in Drosophila melanogaster: comparison of genes with and without insertions.
    Proc Natl Acad Sci U S A. 1981 Mar;78(3):1513-7 PMID: 6262809
  34. Site-specific cleavage by T1 RNase of U-1 RNA in u-1 ribonucleoprotein particles.
    Proc Natl Acad Sci U S A. 1981 Mar;78(3):1562-6 PMID: 6165013
  35. Nucleotide sequence of Escherichia coli trpE. Anthranilate synthetase component I contains no tryptophan residues.
    J Mol Biol. 1981 Feb 15;146(1):45-54 PMID: 7021857
Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
DOI
10.1093/nar/10.1.449
Published
1982-01-11
Pages
449-56
Language
English
Region
England
NLM ID
0411011
PMCID
PMC326145
Subset
IM
External Links
PubMed source DOI: 10.1093/nar/10.1.449 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2