Abstract
Purified RNase III of Escherichia coli cleaved the initial 479-nucleotide sequence of lac operon mRNA at four specific sites and also gave limited cleavage of trp operon mRNA. This action explains the inactivation of mRNA coding capacity by RNase III in vitro.
MeSH Terms
Base Sequence
Endonucleases/metabolism
Escherichia coli/metabolism
Escherichia coli Proteins
Lac Operon
Operon
RNA, Bacterial/genetics,metabolism
RNA, Messenger/genetics,metabolism
Ribonuclease III
Ribonucleases/metabolism
Tryptophan/biosynthesis
beta-Galactosidase/genetics
Chemicals
Escherichia coli Proteins
RNA, Bacterial
RNA, Messenger
Tryptophan
Endonucleases
Ribonucleases
Ribonuclease III
ribonuclease III, E coli
beta-Galactosidase
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Shen V
Imamoto F
Schlessinger D
References (12)
12 references, click to expand
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