Contractile effects of okadaic acid, a novel ionophore-like substance from black sponge, on isolated smooth muscles under the condition of Ca deficiency.

Adenosine Triphosphatases/metabolism Animals Aorta, Thoracic/drug effects Calcium/physiology Cecum/drug effects Ethers, Cyclic/pharmacology Female Guinea Pigs Humans In Vitro Techniques Ionophores/pharmacology Male Muscle Contraction/drug effects Muscle, Smooth/drug effects Muscle, Smooth, Vascular/drug effects Okadaic Acid Pregnancy Rabbits Umbilical Arteries/drug effects

Ethers, Cyclic Ionophores Okadaic Acid Adenosine Triphosphatases Calcium