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PMID: 6221695 Published · ppublish English Comparative Study Journal Article Research Support, U.S. Gov't, P.H.S.

Comparative in vitro study of teichomycin A2.

Antimicrobial agents and chemotherapy ·Vol. 23 ·No. 3 ·1983-03-00 ·Pages 497-9

Fainstein V, LeBlanc B, Bodey GP

Abstract

Teichomycin A2 was evaluated in vitro against clinical isolates, and its activity was compared with that of other antibiotics. This compound was very active against all organisms tested; its activity was comparable to that of vancomycin, and it was superior to several other antibiotics when tested against gram-positive cocci. Because of its in vitro activity, it deserves clinical evaluation.

MeSH Terms

Anti-Bacterial Agents/pharmacology Bacteria/drug effects Microbial Sensitivity Tests Teicoplanin

Chemicals

Anti-Bacterial Agents Teicoplanin

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Fainstein V

LeBlanc B

Bodey G P

References (8)

8 references, click to expand

Beta-lactam antibiotics alone or in combination with gentamicin for therapy of gram-negative bacillary infections in neutropenic patients.
Am J Med Sci. 1976 Mar-Apr;271(2):179-86 PMID: 773180
Teichomycins, new antibiotics from Actinoplanes teichomyceticus nov. sp. II. Extraction and chemical characterization.
J Antibiot (Tokyo). 1978 Mar;31(3):170-7 PMID: 649512
Teichomycins, new antibiotics from Actinoplanes teichomyceticus Nov. Sp. I. Description of the producer strain, fermentation studies and biological properties.
J Antibiot (Tokyo). 1978 Apr;31(4):276-83 PMID: 659325
Comparison of the in vitro activities of teichomycin A2 and vancomycin against staphylococci and enterococci.
Antimicrob Agents Chemother. 1982 Mar;21(3):504-5 PMID: 6213192
Bacteremia due to gram-positive cocci in patients with neoplastic disease.
Am J Med. 1979 Apr;66(4):596-602 PMID: 433966
Bacteremia due to Staphylococcus aureus in patients with cancer: report on 45 cases in adults and review of the literature.
Rev Infect Dis. 1982 Jan-Feb;4(1):1-12 PMID: 7041221
Comparative in vitro study of SQ26,776.
Antimicrob Agents Chemother. 1982 Feb;21(2):294-8 PMID: 6918206
Increasing incidence of Gram-positive sepsis in cancer patients.
Med Pediatr Oncol. 1978;5(1):241-4 PMID: 745589

Article Info

Journal

Antimicrobial agents and chemotherapy

Abbr.

Antimicrob Agents Chemother

ISSN

0066-4804

DOI

10.1128/AAC.23.3.497

Published

1983-03-00

Pages

497-9

Language

English

Region

United States

NLM ID

0315061

PMCID

PMC184679

Subset

Grants

NCI NIH HHS · CA 05831 · United States

External Links

PubMed source DOI: 10.1128/AAC.23.3.497 PMC Full Text View journal details

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Comparative in vitro study of teichomycin A2.

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