The 5' end of foot-and-mouth disease virion RNA contains a protein covalently linked to the nucleotide pUp.

Archives of virology ·Vol. 63 ·No. 3-4 ·1980-00-00 ·Pages 311-5

Grubman MJ

Abstract

Foot-and-mouth disease (FMD) virion RNA contains a protein covalently linked to its 5' end. This protein has a molecular weight of approximately 12,000 daltons and is linked to the nucleotide pUp.

MeSH Terms

Aphthovirus/analysis Chemical Phenomena Chemistry Molecular Weight RNA, Viral/analysis Uridine Diphosphate Viral Proteins/analysis Virion/analysis

Chemicals

RNA, Viral Viral Proteins Uridine Diphosphate

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Grubman M J

References (16)

16 references, click to expand

Structural difference between the 5' termini of viral and cellular mRNA in poliovirus-infected cells: possible basis for the inhibition of host protein synthesis.
J Virol. 1976 May;18(2):719-26 PMID: 178904
Foot-and-mouth disease virion RNA: studies on the relation between the length of its 3'-poly(A) segment and infectivity.
Virology. 1979 Aug;97(1):22-31 PMID: 224578
Encephalomyocarditis virus RNA. III. Presence of a genome-associated protein.
J Virol. 1978 Jan;25(1):413-5 PMID: 202751
CHEMICAL PHYSICAL PROPERTIES OF VIRTUALLY PURE FOOT-AND-MOUTH DISEASE VIRUS.
Am J Vet Res. 1964 Mar;25:333-42 PMID: 14125897
In vitro translation of mengovirus RNA deprived of the terminally-linked (capping?) protein.
FEBS Lett. 1978 Dec 15;96(2):306-12 PMID: 215460
5'-terminal structure of poliovirus polyribosomal RNA is pUp.
Proc Natl Acad Sci U S A. 1976 Feb;73(2):327-30 PMID: 174102
Cell-free translation of foot-and-mouth disease virus RNA into identifiable non-capsid and capsid proteins.
J Gen Virol. 1976 Sep;32(3):383-94 PMID: 61250
Isolation of foot-and-mouth disease virus messenger RNA from membrane-bound polyribosomes and characterization of its 5' and 3' termini.
Virology. 1979 Oct 30;98(2):466-70 PMID: 228483
Ribosomal factors effecting the stimulation of cell-free protein synthesis in the prescence of foot-and-mouth disease virus ribonucleic acid.
Biochem Biophys Res Commun. 1971 Oct 1;45(1):14-21 PMID: 4334521
An enzymatic activity in uninfected cells that cleaves the linkage between poliovirion RNA and the 5' terminal protein.
Cell. 1978 Dec;15(4):1439-46 PMID: 215328
Protein covalently linked to foot-and-mouth disease virus RNA.
Nature. 1977 Aug 18;268(5621):648-50 PMID: 197422
Protein is linked to the 5' end of poliovirus RNA by a phosphodiester linkage to tyrosine.
J Biol Chem. 1978 Aug 10;253(15):5263-6 PMID: 209034
The genome-linked protein of picornaviruses. IV. Difference in the VPg's of encephalomyocarditis virus and poliovirus as evidence that the genome-linked proteins are virus-coded.
Virology. 1978 Aug;89(1):112-8 PMID: 210567
Covalent linkage of a protein to a defined nucleotide sequence at the 5'-terminus of virion and replicative intermediate RNAs of poliovirus.
Proc Natl Acad Sci U S A. 1977 Mar;74(3):961-5 PMID: 191841
The 5' end of poliovirus mRNA is not capped with m7G(5')ppp(5')Np.
Proc Natl Acad Sci U S A. 1976 Feb;73(2):375-80 PMID: 174106
The location of the polio genome protein in viral RNAs and its implication for RNA synthesis.
Nature. 1977 Jul 21;268(5617):208-13 PMID: 196204

Article Info

Journal

Archives of virology

Abbr.

Arch Virol

ISSN

0304-8608

DOI

10.1007/BF01315038

Published

1980-00-00

Pages

311-5

Language

English

Region

Austria

NLM ID

7506870

Subset

External Links

PubMed source DOI: 10.1007/BF01315038 View journal details

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The 5' end of foot-and-mouth disease virion RNA contains a protein covalently linked to the nucleotide pUp.

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