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PMID: 624722 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts incubated with compactin (ML-236B), a competitive inhibitor of the reductase.

The Journal of biological chemistry ·Vol. 253 ·No. 4 ·1978-02-25 ·Pages 1121-8

Brown MS, Faust JR, Goldstein JL, Kaneko I, Endo A

Abstract

暂无摘要

MeSH Terms

Anti-Bacterial Agents/pharmacology Binding, Competitive Cells, Cultured Cholesterol/biosynthesis Enzyme Induction/drug effects Fibroblasts/enzymology Humans Hydroxymethylglutaryl CoA Reductases/biosynthesis Kinetics Lovastatin/analogs & derivatives Naphthalenes/pharmacology Penicillium Skin/enzymology

Chemicals

Anti-Bacterial Agents Naphthalenes mevastatin Cholesterol Lovastatin Hydroxymethylglutaryl CoA Reductases

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Brown M S

Faust J R

Goldstein J L

Kaneko I

Endo A

Article Info

Journal

The Journal of biological chemistry

Abbr.

J Biol Chem

ISSN

0021-9258

Published

1978-02-25

Pages

1121-8

Language

English

Region

United States

NLM ID

2985121R

Subset

External Links

PubMed source View journal details

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Induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts incubated with compactin (ML-236B), a competitive inhibitor of the reductase.

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