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PMID: 6260741 Published · ppublish English Comparative Study Journal Article

Effect of gyrB-mediated changes in chromosome structure on killing of Escherichia coli by ultraviolet light: experiments with strains differing in deoxyribonucleic acid repair capacity.

Journal of bacteriology ·Vol. 146 ·No. 1 ·1981-04-00 ·Pages 18-23

von Wright A, Bridges BA

Abstract

Mutations at the gyrB locus were found to decrease the degree of supercoiling of the Escherichia coli chromosome. The effect of a gyrB mutation on the repair of ultraviolet-induced deoxyribonucleic acid damage was studied by following the killing of strains of E. coli K-12 proficient and deficient in deoxyribonucleic acid repair. The effectiveness of both excision and postreplication types of deoxyribonucleic acid repair was found to be altered by this mutation, the former being apparently enhanced and the latter impaired.

MeSH Terms
Chromosomes, Bacterial/analysis DNA Repair DNA Topoisomerases, Type II/genetics DNA, Bacterial/genetics DNA, Superhelical/genetics Escherichia coli/genetics,radiation effects Mutation Ultraviolet Rays
Chemicals
DNA, Bacterial DNA, Superhelical DNA Topoisomerases, Type II
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
von Wright A
Bridges B A
References (16)
16 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
Published
1981-04-00
Pages
18-23
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC217046
Subset
IM
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