Differences between germ-line and rearranged immunoglobulin V kappa coding sequences suggest a localized mutation mechanism.

Animals Base Sequence Binding Sites, Antibody/genetics Cell Line Cloning, Molecular DNA Restriction Enzymes DNA, Recombinant Genes Immunoglobulin J-Chains/genetics Immunoglobulin Light Chains/genetics Immunoglobulin Variable Region/genetics Immunoglobulin kappa-Chains/genetics Mice Mutation Plasmacytoma

DNA, Recombinant Immunoglobulin J-Chains Immunoglobulin Light Chains Immunoglobulin Variable Region Immunoglobulin kappa-Chains DNA Restriction Enzymes