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PMID: 6264382 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Inhibition of transient outward current by intracellular ion substitution unmasks slow inward calcium current in cardiac Purkinje fibers.

Pflugers Archiv : European journal of physiology ·Vol. 390 ·No. 1 ·1981-04-00 ·Pages 102-6

Marban E

Abstract

暂无摘要

MeSH Terms
Animals Calcium/physiology Cattle Cesium/physiology Electric Conductivity Gallopamil/pharmacology Heart Conduction System/physiology Ion Channels/physiology Manganese/pharmacology Nystatin/pharmacology Potassium/physiology Purkinje Fibers/physiology
Chemicals
Ion Channels Nystatin Cesium Gallopamil Manganese Potassium Calcium
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Marban E
References (25)
25 references, click to expand
  1. Outward membrane currents activated in the plateau range of potentials in cardiac Purkinje fibres.
    J Physiol. 1969 Jan;200(1):205-31 PMID: 5761944
  2. Properties of two inward membrane currents in the heart.
    Annu Rev Physiol. 1979;41:413-24 PMID: 373598
  3. Influence of chloride, potassium, and tetraethylammonium on the early outward current of sheep cardiac Purkinje fibers.
    J Gen Physiol. 1979 Feb;73(2):117-38 PMID: 438768
  4. Heart: excitation-contraction coupling.
    Annu Rev Physiol. 1977;39:201-20 PMID: 322598
  5. Equilibrium dialysis of ions in nystatin-treated red cells.
    Nat New Biol. 1973 Jul 11;244(132):47-9 PMID: 4515993
  6. Calcium-activated transient outward current in calf cardiac Purkinje fibres.
    J Physiol. 1980 Feb;299:485-506 PMID: 6770079
  7. Inactivation without facilitation of calcium conductance in caesium-loaded neurones of Aplysia.
    Nature. 1978 May 25;273(5660):312-4 PMID: 652038
  8. A membrane current related to the plateau of the action potential of Purkinje fibers.
    Pflugers Arch. 1968;303(2):108-23 PMID: 5692850
  9. 4-Aminopyridine and the early outward current of sheep cardiac Purkinje fibers.
    J Gen Physiol. 1979 Feb;73(2):139-57 PMID: 220376
  10. Inward membrane currents in mammalian myocardium.
    Pflugers Arch. 1972;334(1):1-23 PMID: 5066332
  11. The dynamic chloride component of membrane current in Purkinje fibers.
    Pflugers Arch Gesamte Physiol Menschen Tiere. 1967;295(3):197-212 PMID: 5241426
  12. K efflux through inward rectifying K channels in voltage clamped Purkinje fibers.
    Pflugers Arch. 1980 Apr;384(3):207-17 PMID: 6251423
  13. On the mechanism of slow calcium channel block in heart.
    Pflugers Arch. 1980 May;385(2):175-9 PMID: 6248838
  14. The voltage clamp and cardiac electrophysiology.
    Circ Res. 1975 Oct;37(4):403-13 PMID: 1182931
  15. VOLTAGE CLAMP TECHNIQUE IN MAMMALIAN CARDIAC FIBRES.
    Pflugers Arch Gesamte Physiol Menschen Tiere. 1964 Jun 9;280:50-62 PMID: 14251605
  16. Inactivation of Ca conductance dependent on entry of Ca ions in molluscan neurons.
    Proc Natl Acad Sci U S A. 1979 Mar;76(3):1497-500 PMID: 286336
  17. The positive dynamic current and its inactivation properties in cardiac Purkinje fibres.
    J Physiol. 1973 Nov;234(3):569-86 PMID: 4764430
  18. The role of the positive dynamic current on the action potential of cardiac Purkinje fibers.
    Jpn J Physiol. 1975;25(6):705-17 PMID: 1226006
  19. Effects of low-chloride solutions on action potentials of sheep cardiac Purkinje fibers.
    J Gen Physiol. 1977 Nov;70(5):635-60 PMID: 201723
  20. Effects of nystatin on membrane conductance and internal ion activities in Aplysia neurons.
    J Membr Biol. 1977 Oct;37(2):137-56 PMID: 926163
  21. The ion permeability induced in thin lipid membranes by the polyene antibiotics nystatin and amphotericin B.
    J Gen Physiol. 1970 Jul;56(1):100-24 PMID: 5514157
  22. The reversible replacement of internal potassium by caesium in isolated turtle heart.
    J Physiol. 1979 Aug;293:525-37 PMID: 501630
  23. Slow inward current and contraction of sheep cardiac Purkinje fibers.
    J Gen Physiol. 1975 Mar;65(3):367-84 PMID: 1117286
  24. Sodium current in single heart muscle cells.
    Nature. 1979 Mar 15;278(5701):269-71 PMID: 423978
  25. Role of intracellular calcium in the transient outward current of calf Purkinje fibres.
    Nature. 1977 Oct 13;269(5629):611-3 PMID: 917108
Article Info
Journal
Pflugers Archiv : European journal of physiology
Abbr.
Pflugers Arch
ISSN
0031-6768
DOI
10.1007/BF00582721
Published
1981-04-00
Pages
102-6
Language
English
Region
Germany
NLM ID
0154720
Subset
IM
Grants
NHLBI NIH HHS · HL-13306 · United States
External Links
PubMed source DOI: 10.1007/BF00582721 View journal details
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