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PMID: 6265492 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Secretion of testosterone-estradiol-binding globulin by a human hepatoma-derived cell line.

The Journal of clinical endocrinology and metabolism ·Vol. 53 ·No. 2 ·1981-08-00 ·Pages 448-9

Khan MS, Knowles BB, Aden DP, Rosner W

Abstract

Using a sensitive radioimmunoassay for testosterone-estradiol-binding globulin (TeBG) we demonstrate that a human hepatoma-derived cell line secretes a protein which: (a) is immunologically indistinguishable from TeBG; (b) has the same Stokes radius as TeBG; (c) is absorbed by concanavalin A in the same way as TeBG in normal plasma.

MeSH Terms
Carcinoma, Hepatocellular/metabolism Cell Line Female Humans Liver Neoplasms/metabolism Male Pregnancy Sex Hormone-Binding Globulin/metabolism
Chemicals
Sex Hormone-Binding Globulin
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Khan M S
Knowles B B
Aden D P
Rosner W
Article Info
Journal
The Journal of clinical endocrinology and metabolism
Abbr.
J Clin Endocrinol Metab
ISSN
0021-972X
DOI
10.1210/jcem-53-2-448
Published
1981-08-00
Pages
448-9
Language
English
Region
United States
NLM ID
0375362
Subset
IM
Grants
NIADDK NIH HHS · AM-11852 · United States
NCI NIH HHS · CA-18470 · United States
NCI NIH HHS · CA-25875 · United States
External Links
PubMed source DOI: 10.1210/jcem-53-2-448 View journal details
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