Activation of T lymphocytes by lectins and carbohydrate-oxidizing reagents viewed as an immunological recognition of cell-surface modifications seen in the context of "self" major histocompatibility complex antigens.

Animals Cell Membrane/immunology Female Galactose Oxidase/pharmacology H-2 Antigens Histocompatibility Antigens Class II Immune Sera/pharmacology Immunosuppression Therapy Lectins/pharmacology Lymphocyte Activation Major Histocompatibility Complex Male Mice Mice, Inbred AKR Mice, Inbred CBA Mitogens/pharmacology Neuraminidase/pharmacology Periodic Acid/pharmacology Protein Biosynthesis T-Lymphocytes/immunology

H-2 Antigens Histocompatibility Antigens Class II Immune Sera Lectins Mitogens Periodic Acid Galactose Oxidase Neuraminidase