Visual-vestibular interaction in the flocculus of the alert monkey. II. Purkinje cell activity.

Experimental brain research ·Vol. 43 ·No. 3-4 ·1981-00-00 ·Pages 349-60

Waespe W, Henn V

Abstract

The activity of Purkinje cells (P-cells) was recorded in the flocculus of alert Rhesus monkeys under different conditions of visual-vestibular stimulation. Stimulations conditions were vestibular, optokinetic, combined and conflicting. About 10--20% of all P-cells were activated in their simple spike activity during conflicting stimulation to the recording side (type I) and gave no response or much less during vestibular stimulation. About half of these P-cells were also activated during optokinetic stimulation to the recording side at velocities above 40--60 deg/s. Simple and complex spike activity behaved in a reciprocal way with overlapping but not identical working ranges. Simple spike modulation was unidirectional, complex spike activity always bidirectional. Modulation of simple spike activity cannot be related to one single parameter of the sensory input or the oculomotor output. The hypothesis is put forward that the vestibular nuclei and the flocculus behave in a complementary fashion in processing visual-vestibular information, the flocculus being specialized for high velocity optokinetic nystagmus and suppression of vestibular nystagmus.

MeSH Terms

Animals Cerebellum/physiology Dominance, Cerebral/physiology Evoked Potentials Eye Movements Macaca mulatta Motion Perception/physiology Neural Inhibition Purkinje Cells/physiology Rotation Synaptic Transmission Vestibular Nuclei/physiology Vestibule, Labyrinth/innervation Visual Pathways/physiology Visual Perception/physiology

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Waespe W

Henn V

References (24)

24 references, click to expand

Impaired suppression of vestibular nystagmus by fixation in cerebellar and noncerebellar patients.
Arch Psychiatr Nervenkr (1970). 1978 Dec 14;226(3):183-99 PMID: 310666
Visual-vestibular interaction in the flocculus of the alert monkey. I. Input activity.
Exp Brain Res. 1981;43(3-4):337-48 PMID: 6266856
Loss of visual suppression of vestibular nystagmus after flocculus lesions.
Brain Res. 1974 Jun 7;72(2):213-24 PMID: 4209081
Conflicting visual-vestibular stimulation and vestibular nucleus activity in alert monkeys.
Exp Brain Res. 1978 Oct 13;33(2):203-11 PMID: 100338
Input-output activity of the primate flocculus during visual-vestibular interaction.
Ann N Y Acad Sci. 1981;374:491-503 PMID: 6978642
Neural design of the cerebellar motor control system.
Brain Res. 1972 May 12;40(1):81-4 PMID: 4338265
Failure of fixation suppression of caloric nystagmus and ocular motor abnormalities.
Arch Neurol. 1980 Jan;37(1):35-8 PMID: 6965345
Impulse discharges from flocculus Purkinje cells of alert rabbits during visual stimulation combined with horizontal head rotation.
Brain Res. 1975 Apr 4;87(1):66-72 PMID: 1078987
Role of primate flocculus during rapid behavioral modification of vestibuloocular reflex. II. Mossy fiber firing patterns during horizontal head rotation and eye movement.
J Neurophysiol. 1978 May;41(3):764-77 PMID: 96226
Adaptive gain control of vestibuloocular reflex by the cerebellum.
J Neurophysiol. 1976 Sep;39(5):954-69 PMID: 1086347
Suppression of vestibular nystagmus.
Ann Neurol. 1977 Feb;1(2):207 PMID: 889309
Role of primate flocculus during rapid behavioral modification of vestibuloocular reflex. I. Purkinje cell activity during visually guided horizontal smooth-pursuit eye movements and passive head rotation.
J Neurophysiol. 1978 May;41(3):733-63 PMID: 96225
[Oculomotor disturbances as cerebellar symptoms in pontine angle tumors. Contralateral diminution of optokinetic nystagmus as early sign of floccular lesions (author's transl)].
Arch Psychiatr Nervenkr (1970). 1977 Feb 23;223(2):117-30 PMID: 300237
Visual tracking and the primate flocculus.
Science. 1975 Sep 19;189(4207):1000-2 PMID: 1083068
Vestibular nuclei activity in the alert monkey during suppression of vestibular and optokinetic nystagmus.
Exp Brain Res. 1979;37(3):581-93 PMID: 118047
Responses of Purkinje cells in rabbit nodulus and uvula to natural vestibular and visual stimuli.
Pflugers Arch. 1976 Nov 30;367(1):1-6 PMID: 1034278
The role of the flocculus of the monkey in saccadic eye movements.
J Physiol. 1979 Sep;294:317-34 PMID: 117100
Visual-vestibular responses in vestibular nuclear neurons in the intact and cerebellectomized, alert cat.
Neuroscience. 1979;4(11):1599-613 PMID: 514510
Adaptive modification of the vestibulo-ocular reflex in rabbits affected by visual inputs and its possible neuronal mechanisms.
Prog Brain Res. 1979;50:757-61 PMID: 551469
Loss of visual suppression of caloric nystagmus in cats.
Acta Otolaryngol. 1979 May-Jun;87(5-6):499-505 PMID: 463521
Interaction of visual and canal inputs on the oculomotor system via the cerebellar flocculus.
Prog Brain Res. 1979;50:695-702 PMID: 551464
Processing of eye movement signals in the flocculus of the monkey.
J Physiol. 1979 Sep;294:349-64 PMID: 117102
Subjective velocity estimation during conflicting visual-vestibular stimulation.
Arch Psychiatr Nervenkr (1970). 1980;228(2):109-16 PMID: 6779780
The role of the flocculus of the monkey in fixation and smooth pursuit eye movements.
J Physiol. 1979 Sep;294:335-48 PMID: 117101

Article Info

Journal

Experimental brain research

Abbr.

Exp Brain Res

ISSN

0014-4819

DOI

10.1007/BF00238377

Published

1981-00-00

Pages

349-60

Language

English

Region

Germany

NLM ID

0043312

Subset

External Links

PubMed source DOI: 10.1007/BF00238377 View journal details

Analysis Services

Visual-vestibular interaction in the flocculus of the alert monkey. II. Purkinje cell activity.

Contact

WeChat Official Account