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PMID: 6269481 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't

In vitro comparison of N-formimidoyl thienamycin, piperacillin, cefotaxime, and cefoperazone.

Antimicrobial agents and chemotherapy ·Vol. 20 ·No. 1 ·1981-07-00 ·Pages 140-3

Tutlane VA, McCloskey RV, Trent JA

Abstract

The antibacterial activity of N-formimidoyl thienamycin was compared with those of cefotaxime, cefoperazone, and piperacillin against 536 clinical aerobic isolates.

MeSH Terms
Aerobiosis Anti-Bacterial Agents/pharmacology Bacteria/drug effects Bacterial Infections/microbiology Cefoperazone Cefotaxime/pharmacology Cephalosporins/pharmacology Humans Imipenem Lactams/pharmacology Penicillins/pharmacology Piperacillin Species Specificity
Chemicals
Anti-Bacterial Agents Cephalosporins Lactams Penicillins Imipenem Cefoperazone Cefotaxime Piperacillin
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Tutlane V A
McCloskey R V
Trent J A
References (13)
13 references, click to expand
  1. In vitro studies of piperacilin, a new semisynthetic penicillin.
    Antimicrob Agents Chemother. 1978 Jun;13(6):944-50 PMID: 677861
  2. In vitro activity of thienamycin.
    Antimicrob Agents Chemother. 1978 Sep;14(3):436-8 PMID: 708019
  3. Thienamycin, a new beta-lactam antibiotic. I. Discovery, taxonomy, isolation and physical properties.
    J Antibiot (Tokyo). 1979 Jan;32(1):1-12 PMID: 761989
  4. Thienamycin: new beta-lactam antibiotic with potent broad-spectrum activity.
    Antimicrob Agents Chemother. 1979 Apr;15(4):518-21 PMID: 380462
  5. Antibacterial activities of a new stabilized thienamycin, N-formimidoyl thienamycin, in comparison with other antibiotics.
    Antimicrob Agents Chemother. 1980 Jun;17(6):912-7 PMID: 6931548
  6. MK0787 (N-formimidoyl thienamycin): evaluation of in vitro and in vivo activities.
    Antimicrob Agents Chemother. 1980 Jun;17(6):993-1000 PMID: 6931549
  7. In vitro antimicrobial activity of cefotaxime, a new cephalosporin.
    Antimicrob Agents Chemother. 1980 Jul;18(1):1-8 PMID: 6251749
  8. Cefotaxime: in vitro activity and tentative interpretive standards for disk susceptibility testing.
    Antimicrob Agents Chemother. 1980 Jul;18(1):88-93 PMID: 6251750
  9. In vitro evaluation of cefoperazone.
    Antimicrob Agents Chemother. 1980 Mar;17(3):423-7 PMID: 6448578
  10. In vitro activity of N-formimidoyl thienamycin (MK0787), a crystalline derivative of thienamycin.
    Antimicrob Agents Chemother. 1980 Oct;18(4):557-61 PMID: 6934707
  11. In vitro activity of N-formimidoyl thienamycin (MK0787).
    Antimicrob Agents Chemother. 1980 Oct;18(4):642-4 PMID: 6934708
  12. In vitro activity of piperacillin, a new semisynthetic penicillin with an unusually broad spectrum of activity.
    Antimicrob Agents Chemother. 1978 Mar;13(3):349-57 PMID: 122518
  13. Piperacillin, a new penicillin active against many bacteria resistant to other penicillins.
    Antimicrob Agents Chemother. 1978 Mar;13(3):358-67 PMID: 122519
Article Info
Journal
Antimicrobial agents and chemotherapy
Abbr.
Antimicrob Agents Chemother
ISSN
0066-4804
DOI
10.1128/AAC.20.1.140
Published
1981-07-00
Pages
140-3
Language
English
Region
United States
NLM ID
0315061
PMCID
PMC181646
Subset
IM
External Links
PubMed source DOI: 10.1128/AAC.20.1.140 PMC Full Text View journal details
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