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PMID: 6281889 Published · ppublish English Journal Article Review

The Alu family of dispersed repetitive sequences.

Science (New York, N.Y.) ·Vol. 216 ·No. 4550 ·1982-06-04 ·Pages 1065-70

Schmid CW, Jelinek WR

Abstract

A family of related sequences that includes approximately 500,000 members is the most prominent short dispersed repeat family in primate and rodent DNA's. The primate sequence is approximately 300 base pairs in length and is composed of two imperfectly repeated monomer units, whereas the rodent repeat consists of only a single monomer. Properties of this repeat sequence, its flanking sequences in chromosomal DNA, and RNA's transcribed from it suggest that it may be a mobile DNA element inserted at hundreds of thousands of different chromosomal locations.

MeSH Terms
Animals Base Sequence Biological Evolution DNA/genetics DNA Transposable Elements Genetic Linkage Muridae/genetics Primates/genetics RNA Polymerase III/metabolism RNA, Heterogeneous Nuclear/genetics Repetitive Sequences, Nucleic Acid Transcription, Genetic
Chemicals
DNA Transposable Elements RNA, Heterogeneous Nuclear DNA RNA Polymerase III
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Schmid C W
Jelinek W R
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
Published
1982-06-04
Pages
1065-70
Language
English
Region
United States
NLM ID
0404511
Subset
IM
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