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PMID: 6289329 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Transposon Tn10 provides a promoter for transcription of adjacent sequences.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 79 ·No. 16 ·1982-08-00 ·Pages 5016-20

Ciampi MS, Schmid MB, Roth JR

Abstract

Promoters located within the Tn10 insertion element cause transcription of "host" sequences adjacent to both ends of the inserted Tn10 element. These promoters are usually not observed in genetic experiments because their transcripts are efficiently terminated at nearby rho-dependent termination sites. The observations presented here provide an explanation for several confusing aspects of transposon behavior and suggest the possibility that many transposons possess promoters that have escaped detection for similar reasons.

MeSH Terms
DNA Transposable Elements Gene Expression Regulation Genes, Bacterial Histidine/genetics Operon Rho Factor/physiology Salmonella typhimurium/genetics Transcription, Genetic
Chemicals
DNA Transposable Elements Rho Factor Histidine
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Ciampi M S
Schmid M B
Roth J R
References (21)
21 references, click to expand
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Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.79.16.5016
Published
1982-08-00
Pages
5016-20
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC346817
Subset
IM
Grants
NIGMS NIH HHS · GM27068 · United States
External Links
PubMed source DOI: 10.1073/pnas.79.16.5016 PMC Full Text View journal details
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