Identification of envelope glycoprotein encoded by env gene of human T-cell leukemia virus.

Envelope gene product of human T-cell leukemia virus was identified as a glycoprotein with an apparent molecular weight of 62,000 daltons, by using rabbit antiserum against a synthetic decapeptide whose structure had been predicted from the nucleotide sequence. Sera from patients with adult T-cell leukemia also reacted with this glycoprotein.