Extracellular action potentials were recorded from rat ventromedial hypothalamic nucleus (VMH) tissue slices in vitro. The identified glucoresponsive and non-glucoresponsive neurons were then visually located and observed by intracellular horseradish peroxidase staining. Glucoresponsive neurons, which were predominantly multipolar, were found near the center of the VMH, while non-glucoresponsive neurons, half of which were bipolar and half multipolar, were found randomly throughout the VMH.
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