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PMID: 6323769 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Deletion of DNA sequence in a nononcogenic variant of Herpesvirus saimiri.

Journal of virology ·Vol. 50 ·No. 2 ·1984-05-00 ·Pages 662-5

Koomey JM, Mulder C, Burghoff RL, Fleckenstein B, Desrosiers RC

Abstract

The 110-kilobase-pair stretch of unique sequence DNA of Herpesvirus saimiri is flanked by highly repetitive DNA. Detailed restriction endonuclease mapping has localized the left junction of repetitive and unique DNA to a 100-base-pair region. H. saimiri 11att, a replication competent nononcogenic variant of strain 11, has a deletion of 2.3 kilobase pairs of sequence information that spans this left junction of repetitive and unique DNA.

MeSH Terms
Animals Aotus trivirgatus Base Sequence Cell Line Chlorocebus aethiops Chromosome Deletion DNA Restriction Enzymes DNA, Viral/genetics Genes, Viral Genetic Variation Herpesvirus 2, Saimiriine/genetics Kidney Oncogenes Virion/genetics
Chemicals
DNA, Viral DNA Restriction Enzymes
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Koomey J M
Mulder C
Burghoff R L
Fleckenstein B
Desrosiers R C
References (18)
18 references, click to expand
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.50.2.662-665.1984
Published
1984-05-00
Pages
662-5
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC255703
Subset
IM
Grants
PHS HHS · 31363 · United States
NCRR NIH HHS · RR00168 · United States
External Links
PubMed source DOI: 10.1128/JVI.50.2.662-665.1984 PMC Full Text View journal details
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