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PMID: 6324077 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Molecular cloning of the human gastrin gene.

Nucleic acids research ·Vol. 11 ·No. 23 ·1983-12-10 ·Pages 8197-203

Kato K, Hayashizaki Y, Takahashi Y, Himeno S, Matsubara K

Abstract

A genomic clone that contains the human gastrin gene was isolated from a human gene library. Restriction endonuclease mapping and DNA sequencing analysis revealed that this gene is about 0.7 kb long, and has an intron. The intron is located at a position that separates the coding region into the peptide region essential for biological activities of gastrin and the non-essential, N-terminal peptide region.

MeSH Terms

Amino Acid Sequence Base Sequence Cloning, Molecular DNA/metabolism DNA Restriction Enzymes DNA, Recombinant/metabolism Gastrins/genetics Genes Humans Nucleic Acid Hybridization

Chemicals

DNA, Recombinant Gastrins DNA DNA Restriction Enzymes

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Kato K

Hayashizaki Y

Takahashi Y

Himeno S

Matsubara K

References (16)

16 references, click to expand

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Article Info

Journal

Nucleic acids research

Abbr.

Nucleic Acids Res

ISSN

0305-1048

DOI

10.1093/nar/11.23.8197

Published

1983-12-10

Pages

8197-203

Language

English

Region

England

NLM ID

0411011

PMCID

PMC326575

Subset

Databases

GENBANK

X00183

External Links

PubMed source DOI: 10.1093/nar/11.23.8197 PMC Full Text View journal details

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Molecular cloning of the human gastrin gene.

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