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PMID: 6328327 Published · ppublish English Journal Article

Reverse gyrase--a topoisomerase which introduces positive superhelical turns into DNA.

Nature ·Vol. 309 ·No. 5970 ·1984-00-00 ·Pages 677-81

Kikuchi A, Asai K

Abstract

An enzymatic activity which converts closed circular DNA into a positively supercoiled form is present in cellular extracts of Sulfolobus, an acidothermophilic archaebacterium. This novel enzyme is a type II DNA topoisomerase and is active only at temperatures greater than 55 degrees C, in the presence of ATP and Mg2+.

MeSH Terms
DNA Topoisomerases, Type I DNA Topoisomerases, Type II/metabolism DNA, Superhelical/biosynthesis Gram-Negative Bacteria/enzymology Hot Temperature Kinetics Plasmids
Chemicals
DNA, Superhelical DNA reverse gyrase DNA Topoisomerases, Type I DNA Topoisomerases, Type II
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Kikuchi A
Asai K
Article Info
Journal
Nature
Abbr.
Nature
ISSN
0028-0836
DOI
10.1038/309677a0
Published
1984-00-00
Pages
677-81
Language
English
Region
England
NLM ID
0410462
Subset
IM
External Links
PubMed source DOI: 10.1038/309677a0 View journal details
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