Excision sequences in the mitochondrial genome of yeast.

Gene ·Vol. 21 ·No. 3 ·1983-03-00 ·Pages 193-202

de Zamaroczy M, Faugeron-Fonty G, Bernardi G

Abstract

We report an analysis of the sequences used in the excision of the mitochondrial genomes of 22 spontaneous and ten ethidium bromide (EtBr)-induced Saccharomyces cerevisiae petite mutants. In all cases, excision sequences were found to be perfect direct repeats, often flanked on one or both sides by regions of patchy homology. Sequences used in the excision of the genomes of spontaneous petites were always located in the AT spacers and GC clusters of intergenic regions of the genome; the GC clusters corresponded to ori and oris sequences, namely to canonical and surrogate origins of DNA replication, respectively. In the case of the ethidium bromide-induced petites, excision sequences were found not only in intergenic sequences, but also in the introns and exons of mitochondrial genes.

MeSH Terms

Base Sequence Chromosome Mapping DNA Replication DNA, Fungal/genetics DNA, Mitochondrial/genetics Genes Mutation Saccharomyces cerevisiae/genetics

Chemicals

DNA, Fungal DNA, Mitochondrial

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

de Zamaroczy M

Faugeron-Fonty G

Bernardi G

Article Info

Journal

Gene

Abbr.

Gene

ISSN

0378-1119

DOI

10.1016/0378-1119(83)90002-1

Published

1983-03-00

Pages

193-202

Language

English

Region

Netherlands

NLM ID

7706761

Subset

Databases

GENBANK

J01488, J01489, J01490, J01491, J01492, J01493, J01494, J01495, J01496, J01497, J01498, J01499, J01500, J01501, J01502, J01503, J01504, J01505, J01506, J01507, J01508, J01509, J01510, J01511, J01512, J01513, J01514, J01515, J01516, J01517, J01518, J01519, J01520, J01521, J01522, J01523

External Links

PubMed source DOI: 10.1016/0378-1119(83)90002-1 View journal details

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Excision sequences in the mitochondrial genome of yeast.

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