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PMID: 6348289 Published · ppublish English Comparative Study Journal Article

Proteus morgani is less frequently associated with urinary tract infections than Proteus mirabilis--an explanation.

Journal of medical microbiology ·Vol. 16 ·No. 3 ·1983-08-00 ·Pages 317-22

Senior BW

Abstract

The metabolic activities of faecal and urinary strains of Proteus morgani and P. mirabilis were compared. Regardless of origin, the generation time of P. morgani strains in urine was approximately twice as long as that of the P. mirabilis strains. Urease synthesis was constitutive in P. morgani strains but required induction with urea in the P. mirabilis strains. In the presence of urea, the P. mirabilis strains liberated ammonia more rapidly and produced alkaline conditions more quickly than P. morgani strains, although they synthesized much less urease. These characteristics may place P. morgani strains at a disadvantage in comparison with P. mirabilis strains in their ability to cause urinary tract infections.

MeSH Terms
Ammonia/metabolism Bacteriuria/microbiology Enzyme Induction Humans Hydrogen-Ion Concentration Proteus/growth & development,metabolism,pathogenicity Proteus mirabilis/growth & development,metabolism,pathogenicity Urea/pharmacology Urease/biosynthesis
Chemicals
Ammonia Urea Urease
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Senior B W
Article Info
Journal
Journal of medical microbiology
Abbr.
J Med Microbiol
ISSN
0022-2615
Published
1983-08-00
Pages
317-22
Language
English
Region
England
NLM ID
0224131
Subset
IM
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