Monoclonal antibodies to Legionella pneumophila serogroup 1: possible applications in diagnostic tests and epidemiologic studies.

Zentralblatt fur Bakteriologie, Mikrobiologie und Hygiene. 1. Abt. Originale A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie = International journal of microbiology and hygiene. A, Medical microbiology, infectious... ·Vol. 255 ·No. 1 ·1983-07-00 ·Pages 91-5

McKinney RM, Thacker L, Wells DE, Wong MC, Jones WJ, Bibb WF

Abstract

Monoclonal antibodies were produced against two strains of Legionella pneumophila serogroup 1. A panel of nine monoclonal antibodies were selected for their unique specificities observed in indirect fluorescent antibody tests with 130 strains of L. pneumophila serogroup 1. One monoclonal antibody was reactive with an antigen possessed by 128 of 130 strains. Two major subgroups were identified and 13 different antigen patterns were observed among the 130 serogroup 1 strains.

MeSH Terms

Animals Antibodies, Monoclonal/immunology Antigens, Bacterial/analysis Fluorescent Antibody Technique Humans Hybridomas Legionella/immunology Legionnaires' Disease/diagnosis Mice Mice, Inbred BALB C Serotyping

Chemicals

Antibodies, Monoclonal Antigens, Bacterial

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

McKinney R M

Thacker L

Wells D E

Wong M C

Jones W J

Bibb W F

Article Info

Journal

Abbr.

Zentralbl Bakteriol Mikrobiol Hyg A

ISSN

0174-3031

Published

1983-07-00

Pages

91-5

Language

English

Region

Germany

NLM ID

8110566

Subset

External Links

PubMed source

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Monoclonal antibodies to Legionella pneumophila serogroup 1: possible applications in diagnostic tests and epidemiologic studies.

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