A morphological assessment of the stimulatory effect of coumarin on macrophages.

British journal of experimental pathology ·Vol. 59 ·No. 1 ·1978-02-00 ·Pages 93-6

Piller NB

Abstract

In examining the migration of macrophages on to subcutaneously implanted coverslips in rats, it was found that coumarin (5-6 benzo-alpha-pyrone) and a preparation (Venalot) containing the former, very significantly increased the total macrophage number as well as the percentage of stimulation on the skin side of the coverslip. For the muscle side, Venalot increased the total numbers and the percentage stimulated while coumarin alone had no effect compared with the control. It remains to be seen whether these stimulated macrophages are also activated.

MeSH Terms

Animals Cell Count/drug effects Cell Movement/drug effects Coumarins/pharmacology Female In Vitro Techniques Macrophages/cytology,drug effects Rats

Chemicals

Coumarins

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Piller N B

References (9)

9 references, click to expand

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Macrophage content of tumours in relation to metastatic spread and host immune reaction.
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Article Info

Journal

British journal of experimental pathology

Abbr.

Br J Exp Pathol

ISSN

0007-1021

Published

1978-02-00

Pages

93-6

Language

English

Region

England

NLM ID

0372543

PMCID

PMC2041321

Subset

External Links

PubMed source PMC Full Text View journal details

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A morphological assessment of the stimulatory effect of coumarin on macrophages.

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