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PMID: 6389510 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Tetracycline resistance element of pBR322 mediates potassium transport.

Journal of bacteriology ·Vol. 160 ·No. 3 ·1984-12-00 ·Pages 1188-90

Dosch DC, Salvacion FF, Epstein W

Abstract

The tetracycline resistance element of plasmid pBR322 partially complements the potassium transport defect of Escherichia coli K-12 mutants having markedly impaired K+ transport. The plasmid increases K+ transport. The Tn10 element does not result in increased transport, demonstrating that the effect is not general for elements that increase resistance to tetracycline.

MeSH Terms
Drug Resistance, Microbial Escherichia coli/drug effects,genetics,metabolism Kinetics Potassium/metabolism,pharmacology R Factors Tetracycline/pharmacology
Chemicals
Tetracycline Potassium
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Dosch D C
Salvacion F F
Epstein W
References (12)
12 references, click to expand
  1. Potassium transport loci in Escherichia coli K-12.
    J Bacteriol. 1971 Nov;108(2):639-44 PMID: 4942756
  2. Detection of an inducible membrane protein associated with R-factor-mediated tetracycline resistance.
    Biochem Biophys Res Commun. 1974 Feb 27;56(4):1060-8 PMID: 4596957
  3. Cation transport in Escherichia coli. VIII. Potassium transport mutants.
    J Gen Physiol. 1976 Mar;67(3):325-41 PMID: 4578
  4. The electrochemical gradient of protons and its relationship to active transport in Escherichia coli membrane vesicles.
    Proc Natl Acad Sci U S A. 1976 Jun;73(6):1892-6 PMID: 6961
  5. On the nature of tetracycline resistance controlled by the plasmid pSC101.
    Cell. 1978 Jan;13(1):73-81 PMID: 340050
  6. Complete nucleotide sequence of the Escherichia coli plasmid pBR322.
    Cold Spring Harb Symp Quant Biol. 1979;43 Pt 1:77-90 PMID: 383387
  7. Active efflux of tetracycline encoded by four genetically different tetracycline resistance determinants in Escherichia coli.
    Proc Natl Acad Sci U S A. 1980 Jul;77(7):3974-7 PMID: 7001450
  8. Selection for loss of tetracycline resistance by Escherichia coli.
    J Bacteriol. 1981 Feb;145(2):1110-1 PMID: 7007341
  9. Positive selection for loss of tetracycline resistance.
    J Bacteriol. 1980 Aug;143(2):926-33 PMID: 6259126
  10. Plasmid-conferred tetracycline resistance confers collateral cadmium sensitivity of E. coli cells.
    Plasmid. 1982 Jul;8(1):86-8 PMID: 6755512
  11. Nucleotide sequence of the Tn10 encoded tetracycline resistance gene.
    Nucleic Acids Res. 1983 Jan 25;11(2):525-39 PMID: 6298728
  12. Revised sequence of the tetracycline-resistance gene of pBR322.
    Gene. 1983 May-Jun;22(2-3):277-80 PMID: 6307828
Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.160.3.1188-1190.1984
Published
1984-12-00
Pages
1188-90
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC215843
Subset
IM
Grants
NIGMS NIH HHS · GM 22323 · United States
External Links
PubMed source DOI: 10.1128/jb.160.3.1188-1190.1984 PMC Full Text View journal details
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