Structure of the nucleosome core particle at 7 A resolution.

Nature ·Vol. 311 ·No. 5986 ·1984-00-00 ·Pages 532-7

Richmond TJ, Finch JT, Rushton B, Rhodes D, Klug A

Abstract

The crystal structure of the nucleosome core particle has been solved to 7 A resolution. The right-handed B-DNA superhelix on the outside contains several sharp bends and makes numerous interactions with the histone octamer within. The central turn of superhelix and H3 . H4 tetramer have dyad symmetry, but the H2A . H2B dimers show departures due to interparticle associations.

MeSH Terms

Animals Cattle DNA, Superhelical Histones Kidney/ultrastructure Macromolecular Substances Nucleosomes/ultrastructure X-Ray Diffraction

Chemicals

DNA, Superhelical Histones Macromolecular Substances Nucleosomes

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Richmond T J

Finch J T

Rushton B

Rhodes D

Klug A

Article Info

Journal

Nature

Abbr.

Nature

ISSN

0028-0836

DOI

10.1038/311532a0

Published

1984-00-00

Pages

532-7

Language

English

Region

England

NLM ID

0410462

Subset

External Links

PubMed source DOI: 10.1038/311532a0 View journal details

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Structure of the nucleosome core particle at 7 A resolution.

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