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PMID: 6499832 Published · ppublish English Journal Article

Analysis of the distribution of charged residues in the N-terminal region of signal sequences: implications for protein export in prokaryotic and eukaryotic cells.

The EMBO journal ·Vol. 3 ·No. 10 ·1984-10-00 ·Pages 2315-8

von Heijne G

Abstract

A statistical analysis of the distribution of charged residues in the N-terminal region of 39 prokaryotic and 134 eukaryotic signal sequences reveals a remarkable similarity between the two samples, both in terms of net charge and in terms of the position of charged residues within the N-terminal region, and suggests that the formyl group on Metf is not removed in prokaryotic signal sequences.

MeSH Terms
Amino Acid Sequence Animals Biological Transport Cells/metabolism Eukaryotic Cells/metabolism Humans Peptides/analysis Prokaryotic Cells/metabolism Protein Sorting Signals
Chemicals
Peptides Protein Sorting Signals
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
von Heijne G
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Article Info
Journal
The EMBO journal
Abbr.
EMBO J
ISSN
0261-4189
Published
1984-10-00
Pages
2315-8
Language
English
Region
England
NLM ID
8208664
PMCID
PMC557686
Subset
IM
External Links
PubMed source PMC Full Text View journal details
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