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PMID: 6517561 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

In vitro susceptibility of anaerobic bacteria to ciprofloxacin (Bay o 9867).

Antimicrobial agents and chemotherapy ·Vol. 26 ·No. 5 ·1984-11-00 ·Pages 785-6

Prabhala RH, Rao B, Marshall R, Bansal MB, Thadepalli H

Abstract

About 80% of 70 clinical isolates of Bacteroides fragilis were inhibited by 4 micrograms of ciprofloxacin (Bay o 9867) per ml. The 90% MIC of ciprofloxacin was 8 micrograms/ml for other Bacteroides species, 2 micrograms/ml for Peptococcus species, 8 micrograms/ml for Peptostreptococcus species, and 16 micrograms/ml for Clostridium and Eubacterium species.

MeSH Terms
Animals Anti-Bacterial Agents/pharmacology Bacteria, Anaerobic/drug effects Ciprofloxacin Humans Mice Microbial Sensitivity Tests Quinolines/pharmacology
Chemicals
Anti-Bacterial Agents Quinolines Ciprofloxacin
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Prabhala R H
Rao B
Marshall R
Bansal M B
Thadepalli H
References (5)
5 references, click to expand
  1. Pharmacokinetics and tissue penetration of ciprofloxacin.
    Antimicrob Agents Chemother. 1983 Nov;24(5):784-6 PMID: 6660852
  2. Isolation of anaerobic bacteria from human gingiva and mouse cecum by means of a simplified glove box procedure.
    Appl Microbiol. 1969 Apr;17(4):568-76 PMID: 4890748
  3. Comparative activities of ciprofloxacin (Bay o 9867), norfloxacin, pipemidic acid, and nalidixic acid.
    Antimicrob Agents Chemother. 1983 Aug;24(2):302-4 PMID: 6227281
  4. In vitro activity of Bay 09867, a new quinoline derivative, compared with those of other antimicrobial agents.
    Antimicrob Agents Chemother. 1983 Apr;23(4):559-64 PMID: 6222695
  5. In vitro activity of ticarcillin against anaerobic bacteria compared with that of carbenicillin and penicillin.
    Antimicrob Agents Chemother. 1977 Feb;11(2):258-61 PMID: 848931
Article Info
Journal
Antimicrobial agents and chemotherapy
Abbr.
Antimicrob Agents Chemother
ISSN
0066-4804
DOI
10.1128/AAC.26.5.785
Published
1984-11-00
Pages
785-6
Language
English
Region
United States
NLM ID
0315061
PMCID
PMC180016
Subset
IM
Grants
NCRR NIH HHS · S06 RR08101-12 · United States
External Links
PubMed source DOI: 10.1128/AAC.26.5.785 PMC Full Text View journal details
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