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PMID: 6617844 Published · ppublish rus Comparative Study English Abstract Journal Article

[Quantitative study of the morphofunctional changes in the placenta of rats exposed to nicotine at various periods of pregnancy].

Kolichestvennoe izuchenie morfofunktsional'nykh izmeneniĭ platsenty krys, podvergshikhsia vozdeĭstviiu nikotina v raznye periody beremennosti.

Farmakologiia i toksikologiia ·Vol. 46 ·No. 4 ·1983-00-00 ·Pages 93-6

Sheina NI

Abstract

Administration of 2% nicotine to Wistar rats in doses of 1.5 and 5 mg/kg produced functional disorders of the placenta over the entire pregnancy. From the 14th to the 21st day it retarded pregnancy, which at a dose of 1.5 mg/kg was made for by the increased area of the trophoblast elements.

MeSH Terms

Animals Dose-Response Relationship, Drug Female Nicotine/pharmacology Placenta/drug effects,physiopathology Pregnancy Pregnancy, Animal/drug effects Rats Rats, Inbred Strains Time Factors Trophoblasts/drug effects

Chemicals

Nicotine

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Sheina N I

Article Info

Journal

Farmakologiia i toksikologiia

Abbr.

Farmakol Toksikol

ISSN

0014-8318

Published

1983-00-00

Pages

93-6

Language

rus

Region

Russia (Federation)

NLM ID

16920420R

Subset

External Links

PubMed source

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[Quantitative study of the morphofunctional changes in the placenta of rats exposed to nicotine at various periods of pregnancy].

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