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PMID: 6626159 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Preparation of a low-density species of endocytic vesicle containing immunoglobulin A.

The Biochemical journal ·Vol. 214 ·No. 3 ·1983-09-15 ·Pages 823-7

Mullock BM, Luzio JP, Hinton RH

Abstract

Immunoglobulin A is transported across hepatocytes in specialized vesicles. A population of endocytic vesicles of approx. 140 nm diameter, containing immunoglobulin A, has now been separated from all other major cytoplasmic organelles, including plasma membrane and lysosomes, by sequential centrifugation on Ficoll/sucrose and Metrizamide gradients.

MeSH Terms
Animals Biological Transport Centrifugation, Isopycnic Endocytosis Immunoglobulin A/metabolism In Vitro Techniques Liver/cytology,immunology Male Microscopy, Electron Organoids/immunology Rats Rats, Inbred Strains
Chemicals
Immunoglobulin A
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Mullock B M
Luzio J P
Hinton R H
References (9)
9 references, click to expand
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  9. Receptor mediated endocytosis of hemoglobin-haptoglobin, galactosylated serum albumin and polymeric IgA by the liver.
    Acta Biol Med Ger. 1982;41(1):113-24 PMID: 6287771
Article Info
Journal
The Biochemical journal
Abbr.
Biochem J
ISSN
0264-6021
DOI
10.1042/bj2140823
Published
1983-09-15
Pages
823-7
Language
English
Region
England
NLM ID
2984726R
PMCID
PMC1152319
Subset
IM
External Links
PubMed source DOI: 10.1042/bj2140823 PMC Full Text View journal details
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